Erectile Dysfunction Statistics

Erectile dysfunction is a common condition that affects a significant
proportion of men worldwide. As recent statistics show, erectile
dysfunction affects approximately 52% of men aged 40–70 years. This
problem makes Cialyn a critical therapeutic. This tendency increases
with age, affecting about 40% of men by age 40 and nearly 70% of men by
age 70. This condition not only impacts the quality of life but also
contributes to psychological stress, anxiety, and depression among
affected patients.

BPH Statistics

In addition to ED, Cialyn is used to treat the symptoms of benign
prostatic hyperplasia (BPH). The condition affects the prostate gland in
men. Older men usually suffer from it, which is approved by studies.
They show that about 50% of men aged 51–60 years and up to 90% of men
older than 80 years experience symptoms of BPH. Symptoms include
difficulty in urination, frequent urination, and urinary retention,
which significantly impact the quality of life.

Usage and Popularity

Cialyn is available in various forms. Patients can take it daily or
upon necessity. Thus, pills come as a versatile option for men with
different lifestyles and needs. The daily version allows for spontaneous
sexual activity without the need to plan ahead. Still, the as-needed
version provides flexibility for those men who prefer to take medication
only when required. Such flexibility acts in favor of the popularity
and widespread use of Cialyn.

Mechanism of Action

PDE5 Inhibition

Cialyn regulates the inhibition of the enzyme phosphodiesterase type 5
(PDE5). The element is present in tissues, and the soft tissues of the
penis are no exception. Phosphodiesterase type 5 is responsible for the
breakdown of cyclic guanosine monophosphate (cGMP) in any organ. The
component is an important ingredient of the drug, as it improves blood
flow in the penis.

cGMP and Smooth Muscle Relaxation

The corpus cavernosum of the male penis releases nitric oxide (NO)
when actively stimulated. The Cialyn component enhances the activity of
the enzyme guanylate cyclase, which in turn increases the content of
cGMP. This process leads to the relaxation of the soft muscle tissue of
the penis, as the enzyme penetrates its cells. With powerful and strong
blood flow, an erection occurs instantly. The medication counteracts the
formation of the PDE5 component at the cellular level. As a result, the
content of the cGMP component increases, and penis hardening due to
intense blood flow naturally improves. This is the restoration of the
organ’s sensitivity to erotic stimulation.

Extended Half-Life

One of the strongest advantages of Cialyn is that it’s not removed
from the body very quickly. The duration of the half-life is almost a
day — approximately 17.5 hours. This fact means that the activity of the
active substances lasts much longer compared to PDE-5 inhibitors such
as vardenafil (Levitra) and sildenafil (Viagra). As a result, the
activity of the active substance lasts up to 36 hours. In this regard,
the medicine is called the “weekend pill”. When taking Cialyn, a man
does not have to worry about the exact timing for a successful erection.
Sexual activity is guaranteed throughout the weekend.

Selectivity for PDE5

Cialyn is a drug with high selectivity in the treatment of PDE5. At
the same time, active ingredients work very effectively and are
absolutely safe for men’s health. The selectivity indicator
significantly reduces the likelihood of side effects and unexpected
reactions from taking the medication. Since PDE5 is found in the soft
tissues of the prostate gland and penis, the tablet is quite effective
in eliminating problems with prostate adenoma and ED.

Detailed Uses

Primary Use: Improving Erectile Function

The main purpose of pills is to treat erectile dysfunction. According
to studies, Cialyn improves hardening and swelling of the penis in men
suffering from lack of sexual arousal. Tadalafil supports a natural
erection with increased blood flow after active stimulation of the
erogenous zone in a natural way. Many years of clinical trials and
practical research confirm and document the beneficial effects of the
drug.

Clinical studies confirm the effectiveness of Cialyn in improving
erectile function in men with various degrees of severity of erectile
dysfunction. As the active component of the tablets, tadalafil acts
specifically to accelerate blood flow through the vessels of the penis
in all patients, regardless of their demographics and the difficulty of
getting an erection. One of the studies examined the effects and safety
of tadalafil. Research was carried out to eliminate mild and severe
problems of the erectile organ. During the observation process, a group
of scientists noted that serious hardening and swelling of the penis
occurs under the condition of therapeutic use of tadalafil. As the drug
was taken, it was found that the component works well in different age
categories of patients and is guaranteed to strengthen erections
regardless of the severity of the disease.

The second direction of clinical trials was carried out to check the
duration of action of the drug, as well as the safety and reliability of
the targeted effect on the patient’s painful areas. As a result, it was
concluded that tadalafil can be used in safe proportions for six
months. Positive results were noted in 80% of male subjects. The drug
testing period allowed us to draw other important conclusions about the
easy and safe tolerability of the ingredient. The expert group concluded
that the drug can be taken in the presence of concomitant diseases. For
example, the action of tadalafil is not affected by high blood
pressure, diabetes, or diseases of the cardiovascular system. It turns
out that the reliability of using the drug for men suffering from these
diseases is equally high and does not depend on the course of chronic
diseases. Cialyn shows a positive result in its targeted effect on
solving the patient’s problem.

Reducing Blood Pressure

Cialyn is designed to eliminate problems with blood flow into the
vessels of the male genital organ. Patients note that the remedy works
well in the fight against hypertension. As a result, instead of one
problem, the drug has a beneficial effect in two directions and is
indicated for men with high blood pressure and erectile dysfunction.
Tadalafil stands as the main active ingredient of the treatment. By its
chemical structure, it’s a phosphodiesterase type 5 (PDE5) inhibitor.
The component gently acts on the elasticity of blood vessels, which
expands and increases the level of cyclic guanosine monophosphate (cGMP)
in smooth muscle cells. The elasticity of the vascular walls indicates
relaxation of the tone. As a result of the dilation of blood vessels,
blood flow increases significantly, and the path remains clear, so the
pressure does not increase. Long-term laboratory studies demonstrate a
decrease in diastolic and systolic blood pressure. Over a long period of
time, even with the gradual removal of Tadalafil from the body, the
elasticity of the vascular walls continues to remain high. In this
regard, Cialyn fights problems with hardening the blood vessels of the
penis, and at the same time improves the well-being of hypertensive
patients.

Improving Tissue Tropism and Prostate Health

Statistical examination of patients who received Tadalafil showed
that the medication promotes free blood flow and tissue tropism. This
fact indicates that men receive additional prospects for improving their
prostate health. Patients receive basic medications for benign
prostatic hyperplasia (BPH). Active ingredients significantly reduce
symptoms due to the gradual relaxation of the muscle tissue of the
bladder and prostate gland. As a result, urine flows out like in healthy
people. It is a known fact that with prostate adenoma, the prostate
gland becomes significantly enlarged and partially blocks the urination
channel. Patients often feel the urge to urinate, urinary retention, and
weak outflow. Cialyn causes a concomitant action, which helps relax the
bladder neck and prostate muscle cells. As a result, treatment of
problems with penile erection leads to an improvement in the condition
of prostate adenoma. Thus, the supplement comes as a unique dual-action
drug for men who have prostate adenoma and poor urine flow.

Workout Enhancement for Bodybuilders

Men who train to build muscles take Cialyn to open up the blood
vessels in the muscles of the arms, legs, and throughout the body by
increasing elasticity and improving blood flow. This circumstance makes
training much easier. PDE inhibition may help improve muscle growth by
allowing greater blood flow to the soft tissue. According to research
results, Tadalafil medications significantly increase endothelial
function and muscle mass. Thanks to this action, the effectiveness of
training increases significantly, which makes the drug beneficial for
bodybuilders.

PDE inhibitors significantly reduce inflammation after gym training
and physical exercise. Medication components contribute to the
consistent and gradual restoration of health and maintain the athletic
shape of any bodybuilder.

Post-Cycle Therapy in Steroid Users

Cialyn has been observed to increase testosterone levels, which can
be used during post-cycle therapy (PCT). Studies have indicated that
PDE5 inhibitors can have a positive effect on serum testosterone levels,
making Cialyn a useful supplement in PCT.

Improving Fertility

Erectile dysfunction can negatively impact fertility by reducing the
frequency and quality of sexual intercourse. Thus, by taking Cialyn, men
manage to improve erectile function, which enhances fertility
indirectly. Moreover, Cialyn consumption improves the quality of sperm
cells and seminal fluid. In particular, it affects motility, the
percentage of nemasperms, and the volume of seminal fluid.

Dosages, Side Effects, and Precautions

Dosages

Cialyn is available in various dosages, ranging from 2.5 mg to 20 mg.
For patients who suffer from erectile dysfunction, the recommended dose
starts from 10 mg. They should take it right before an expected sexual
activity. However, note that the dosage can be adjusted, depending on
efficacy and tolerability. If men prefer to take the treatment daily, a
lower dose of 2.5 mg or 5 mg is recommended.

Dosage Adjustments

Depending on patients’ individual response and tolerance, some men
require Cialyn dosage adjustment. Some men need a lower dose of 5 mg to
achieve the desired effect, while others may require a maximum dose of
20 mg. Thus, dosages are adjustable and depend on the severity of the
condition and individual characteristics of the body.

Side Effects

The treatment is generally beneficial, but some side effects are still reported. Thus, Cialyn may cause the following drawbacks:

1. About 15% of patients have mild headaches.
2. Approximately 10% of consumers have flushing effects, which causes a temporary redness of the face and neck.
3. About 5% of users experience back pain. Typically, pain is mild to moderate in severity.
4. Nasal congestion is observed in about 5% of cases and is usually resolved without treatment.

More serious side effects, although rare, include:

1. Vision changes, such as blurred vision or a blue tinge to vision.
2. Hearing loss. It may be a sudden decrease or loss of hearing.
3. Priapism. It’s a condition when an erection lasts longer than four hours. It can cause permanent damage if not treated promptly.

Precautions

Individuals who have problems with the cardiovascular system should
take the medication with caution, as it can interact with nitrates and
cause a significant drop in blood pressure. When consulting a physician
about consuming Cialyn, it’s important to disclose all medications and
supplements to avoid potential drug interactions. Patients with severe
liver or kidney damage should use Cialyn under strict medical
supervision.

Drug Interactions

Cialyn can interact with several medications, including:

1. Nitrates. They are often used for chest pain (angina), which can lead to a dangerous drop in blood pressure.
2. Alpha-blockers. Such medications are used to treat high blood
   pressure and BPH, which can also cause a significant drop in blood
   pressure.
3. Antihypertensives. Drugs are used to treat high blood pressure, requiring careful monitoring to avoid hypotension.

Special Populations

The following categories of people should take Cialyn with caution:

• Elderly patients. Aged men’s bodies are more sensitive to the effects of Cialyn, which is why they may require dose adjustments.
• Patients with hepatic impairment. Constant monitoring of their body’ conditions is required due to altered drug metabolism.
• Patients with renal impairment. They may require dose adjustments, depending on kidney function.

How to Store?

• Keep away from children.
• Keep in a cool, dry place, away from direct sunlight.
• Store at room temperature.
• Do not use it after the expiry date.

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FAQ

How many hours does Tadalafil last?

The average duration of the product’s effect is 17.5 hours.

When is the best time to take Tadalafil?

The answer depends on the treatment method. If you consume the drug
on a daily basis, then you should take pills regularly at the same time
of the day. If you prefer at-need consumption, it’s better to take pills
at least half an hour (or better an hour) before an expected sexual
activity to guarantee sufficient strength of the penis.